{"id":178,"date":"2019-10-14T13:29:37","date_gmt":"2019-10-14T13:29:37","guid":{"rendered":"http:\/\/sites.une.edu\/research\/?p=178"},"modified":"2020-05-27T17:31:25","modified_gmt":"2020-05-27T17:31:25","slug":"une-faculty-showcase-research-at-national-bone-meeting","status":"publish","type":"post","link":"https:\/\/sites.une.edu\/research\/une-faculty-showcase-research-at-national-bone-meeting\/","title":{"rendered":"UNE Faculty Showcase Research at National Bone Meeting"},"content":{"rendered":"\n
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Tamara King, Ph.D., associate professor of Physiology, College of Osteopathic Medicine<\/em> <\/figcaption><\/figure><\/div>\n\n\n\n

We often think of bones as simple structures that the body\nis built around. On the contrary, bone biology and bone health are dynamic\nprocesses that impact the health and well-being across the lifespan.\nUnderstanding bone function and factors which impact bone health is a growing\narea of research interest at UNE and is part of a vital collaborative effort\nbetween researchers at UNE and Maine Medical Center Research Institute in\nScarborough.  Work from these researchers\nwere on display at the 2019 annual meeting for the American Society for Bone\nand Mineral Research (ASBMR), held in Orlando Florida (September 20-23).  <\/p>\n\n\n\n

The ASBMR meeting, which hosted approximately 3000 attendees\nfrom more than 70 countries, focuses on basic, translational and clinical\nscience relating to bone biology and bone health and attracts scientists, and\nclinicians representing all career levels and specializing in a variety of\ndisciplines including medicine, dentistry, geriatrics, oncology and others. <\/p>\n\n\n\n

A highlight of the meeting was a special session devoted to bone\npain.  In that session UNE faculty\nmember, Tamara King, Ph.D., associate professor COM, presented an invited\nkeynote address entitled \u201cMechanistic Analysis of Bone Pain\u201d in which she\nshared her expertise as a pain researcher to highlight approaches to assess\nbone pain associated with osteoarthritis, cancer, osteoporosis and TMJ. <\/p>\n\n\n\n

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In addition to Dr. King, UNE faculty in attendance were Kathleen Becker, Ph.D., assistant professor COM and Karen Houseknecht, Ph.D., associate provost for Research and Scholarship. Collectively they co-authored 6 abstracts that were presented at the meeting, in collaboration with UNE students and with bone researchers at Maine Medical Center Research Institute.<\/p>\n\n\n\n

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Left to right: Tamara King, Ph.D., Karen Houseknecht, Ph.D., and Kathleen Becker, Ph.D. attending the annual American Society for Bone and Mineral Research meeting. <\/em> <\/figcaption><\/figure><\/div>\n\n\n\n

Back at UNE, King, Becker and Houseknecht are joined by Meghan\nMay, Ph.D. in an inter-disciplinary group of researchers who came together\nsomewhat organically to work on projects involved bone biology and\nfunction.  King, a pain researcher,\nHouseknecht, an endocrinology\/pharmacology researcher, Becker, a bone\nbiologist, and May, an infectious disease expert, call themselves the \u201cBone\nPosse.\u201d They are trained in vastly different specialties yet have been working\ntogether to deepen their research on bone health and function, with exciting\nresults. The transdisciplinary nature of the group allows the labs to tackle\n\u201cbig\u201d questions such as:  How is bone\npain regulated with osteoporosis? How do psychiatric drugs regulate the immune\nsystem? How do medications increase susceptibility to bone loss and bone pain? <\/p>\n\n\n\n

In addition to strengthening research efforts through\ncombining unique tools, strengths and expertise, this collaboration affords\nadditional opportunities for UNE students and post-doctoral scientists to learn\nnew techniques and interact with leading experts across multiple institutions. Undergraduate\nand medical students, as well as graduate students pursuing their PhD, have\nworked on \u201cBone Posse\u201d research projects. This summer also included visiting\nstudents including an INBRE scholar from SMCC and a graduate student from the\nUniversity of Granada (Spain).  The\nstudents have presented their research at local, national, and international\nmeetings, giving them important opportunities to present their work and build\ntheir resumes and professional networks. By working together, UNE\u2019s \u201cBone\nPosse\u201d harnesses the transdisciplinary power of diverse expertise to publish\nbroadly-read research articles, generate innovative grant proposals, create\nopportunities for students, and most importantly, address big questions in bone\nbiology and human health.<\/p>\n\n\n\n

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Back Row<\/em><\/strong>: Eryn Harrington, (student intern, North Carolina State), Kathleen Becker, Ph.D., (assistant professor College of Osteopathic Medicine), Kristin Gaudreau (Medical Biology, \u201819), Kaylee Townsend (Medical Biology and English, \u201821), Matthew Slitzky (Osteopathic Medicine \u201822), Bahman Rostama, Ph.D., (research associate, College of Osteopathic Medicine), Joshua Havelin, M.S., (doctoral student \u201920), Andrew Elkinson (Medical Biology, \u201820)<\/em>
Third Row<\/em><\/strong>: Victoria Eaton, B.S., (laboratory technician and manager, College of Osteopathic Medicine), Karen Houseknecht, Ph.D., (associate provost of Research and Scholarship and professor, College of Osteopathic Medicine), Deborah Barlow, B.S., (research technician III, Office of Research and Scholarship), Mar\u00eda Caama\u00f1o Sanchez (master\u2019s student, University of Granada, Spain), Jumana Al-Hanfy (INBRE Scholar from SMCC)<\/em>
Second Row:<\/em><\/strong> Tamara King, Ph.D. (associate professor, College of Osteopathic Medicine), Meghan May, Ph.D., (associate professor, College of Osteopathic Medicine)<\/em>
First Row:<\/em><\/strong> Elliott Hall <\/em> <\/figcaption><\/figure>\n\n\n\n




ASMBR Abstract Citations:<\/strong>

<\/p>\n\n\n\n

Antipsychotic induced bone loss: Impact on osteoporosis-associated back pain *Victoria Eaton<\/strong>1<\/strong><\/sup>, Andrew Elkinson<\/strong>1<\/strong><\/sup>, Joshua Havelin<\/strong>1<\/strong><\/sup>, Karen Houseknecht<\/strong>1<\/strong><\/sup>, Tamara King<\/strong>1<\/strong><\/sup>.
1 University of New England, United States

Morphine Treatment Reduces Trabecular Bone Volume Fraction and Impairs Cortical Bone Expansion in Male Mice *Adriana Lelis Carvalho1<\/sup>, Breanna Morrill1<\/sup>, Katherine Motyl1<\/sup>, Deborah Barlow<\/strong>2<\/strong><\/sup>, Karen Houseknecht<\/strong>2<\/strong><\/sup>, Tamara King<\/strong>2<\/strong><\/sup>.
1 Maine Medical Center Research Institute (MMCRI), United States
2 University of New England (UNE), United States

Housing temperature influences bone and brown adipose tissue side effects of atypical antipsychotic drugs in female mice *Audrie Langlais1<\/sup>, Katherine J. Motyl1<\/sup>, Roni F. Kunst2<\/sup>, Karen Houseknecht<\/strong>3<\/strong><\/sup>.
1 Maine Medical Center Research Institute, United States
2 Maine Medical Center Research Institute, United States
3 University of New England, United States

Deletion Diminishes Bone Material Properties and Osteocytes Dendrite Morphologies. *Jennifer Coulombe1<\/sup>, Virginia Ferguson1<\/sup>, Eben Estell2<\/sup>, Kathleen Becker<\/strong>2<\/strong><\/sup>, Vanessa Sherk3<\/sup>, Clifford Rosen4<\/sup>.
1 Department of Mechanical Engineering, University of Colorado Boulder, United States
2 Maine Medical Center Research Institute, United States
3 Department Orthopedics, University of Colorado Anschutz Medical Campus, United States
4 Tufts University School of Medicine, Maine Medical Center Research Institute, United States

Association of Beta Blocker Use and Bone Mineral Density using the Framingham Osteoporosis Study: Effects of Dose, Duration, and Drug *Christine Lary1<\/sup>, Kathleen Nevola1<\/sup>, Alexandra Hinton1<\/sup>, Katherine Motyl1<\/sup>, Lee Lucas1<\/sup>, Sarah Hallen1<\/sup>, Theresa Shireman2<\/sup>, Andrew Zullo2<\/sup>, Karen Houseknecht<\/strong>3<\/strong><\/sup>, Sarah Berry4<\/sup>, Douglas Kiel4<\/sup>.
1 Maine Medical Center Research Institute, United States
2 Brown University School of Public Health, United States
3 University of New England, United States
4 Harvard Medical School, United States<\/p>\n\n\n\n

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